PRODUCT NAME: Oxana
CONTENT: 30 Tabs/10mg
MANUFACTURER: Doramex/Northern Marina Islands
Oxandrolone is a oral steroid
Oxandrolone is also a 17alpha alkylated oral steroid, carrying an alteration that is noted for putting stress on the liver. It is important to point out however that to spite this alteration this drug is generally very well tolerated. While liver enzyme tests will occasionally show elevated values, actual damage due to Oxandrolone is not a statistical problem. Bio-Technology General states that this substance is not as extensively metabolized by the liver as other 1 7aa orals are; evidenced by the fact that nearly a third of product is still intact when excreted in the urine. This may have to do with the understood mHder nature of Oxandrolone (compared to other 1 7aa orals) in terms of hepatotoxicity. One study comparing the effects of Oxandrolone to other agents including as methyltestosterone, norethandrolone, fluoxymesterone and methandriol clearly supports this notion. Here it was demonstrated that the steroid causes the lowest sulfobromophthalein (BSP; a marker of liver stress) retention among all the alkylated orals tested. 20mg of Oxandrolone in fact produced 72% less BSP retention than an equal dosage of fluoxymesterone, which is a considerable difference being that they possess the same liver-toxic alteration. With such findings, combined with the fact that athletes rarely report trouble with Oxandrolone, most feel comfortable believing it to be much safer to use during longer cycles than most of other orals with this distinction. Although this may very well be true, the chance of liver damage still cannot be excluded however.
Other abilities of Oxandrolone
At one time Oxandrolone was also looked at as a possible drug for those suffering from disorders of high cholesterol or triglycerides. Early studies showed that substance to be capable of lowering total cholesterol and triglyceride values in certain types of hyperlipidemic patients, which initially this was thought to signify potential for Oxandrolone as a hypo-lipid (lipid lowering) agent. With further investigation we find however that while use of this steroid can be linked to a lowering of total cholesterol values, it is such that a redistribution in the ratio of good (HDL) to bad (LDL) cholesterol occurs, usually moving values in an unfavorable direction. This would of course negate any positive effect that Oxandrolone might have on triglycerides or total cholesterol, and in fact make it a danger in terms of cardiac risk when taken for prolonged periods of time. Today we understand that as a group anabolic/androgenic steroids produce very unfavorable changes in lipid profiles, and are really not useful in disorders of lipid metabolism. As an oral c17 alpha alkylated steroid, Oxandrolone is even more risky to use than an injectable esterified injectable such as a testosterone or nandrolone in t regard.
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