Category: Oral Steroids
Active substance: Oxandrolone
Chemical Name: Oxandrolone
Manufacturer: Generics Pharm, Europe
Pack: 30 pills (10 mg/pill)
Active Life: 8-12 hours
Average Dose: Men 30-60 mg/day......Women 5-15 mg/day
DHT Conversion: Low
Decrease HPTA function: Dose depandant
Anavar by Generics Pharm: effects, dosages, cycles and side effects
Anavar is an orally applicable steroid manufactured by Generics Pharm, Bulgaria and containing Oxandrolone which is a potent Dihydrotestosterone (DHT) derived anabolic steroid of high popularity. Discovered in the 60s Oxandrolone is widely used due to its exceptionally small androgenic level of and a moderate anabolic effect. It treats the fighting muscle wasting diseases or osteoporosis, and other conditions. Anavar comes in boxes, each unit containing 30 pills (10 mg/pill).
Anavar offers important achievements in strength without gaining body weight. It is also one of the leading steroids in therapeutic steroidal treatment. This steroid is ideal for bulking purposes and it is commonly used during cutting phases of training. Anavar is non-aromatization steroid, it is important for use in cutting purposes destined to enhance the athletic performance. Oxandrolone is very popular and efficient among female athletes and Anavar lately became one of the most used anabolic steroid among women. Even if Oxandrolone is a 17-alpha alkylated steroid its level of toxicity on the liver is much lower than of other compounds.
Anavar has a relatively short life – about 8 hours and it should be taken 2 to 3 times daily after meals thus assuring an optimal absorption of the substance. Male bodybuilders use Anavar in doses of 50-100 mg a day; women take a dosage of 2.5-10mgs to be effective for promoting muscle gains and strength without the great risk of side effects. Oxandrolon as sole taken steroid does not cause significant muscle growth or strength. It can be combined with many steroids like Deca Durabolin, Dianabol and various testosterone compounds. A combination that has been proven to be very effective is Anavar and Halotestin 20 - 30 mg per day or Anavar with 120 – 140 mcg of Clenbuterol daily.
An Anavar cycle varies from 6 to 12 weeks for men with 50-100 mg per day. A cycle may last from 6 to 8 weeks for women and children. Female users often achieve incredible results from 5-10mgs/day of Oxandrolone alone. A clearly efficient cycle would be to use Anavar per day in the first eight weeks, followed by Testosterone Propionate, Primobolan and Nolvadex in the following weeks.
Anavar has just a few side effects, one of them being the 17-alpha-alkylated action on the liver, but only when high dosage and excided long term use. Women should not take more than 50-60 mg daily otherwise there may occur several androgenic-caused side effects as clitorial hypertrophy, acne, deep voice, or increased body and face hair growth.
Oxandrolone Brand Names
Oxanodex, Oxandrol, Anavar, Oxanabol, Oxandrin, Oxan, Bonavar, Oxandroxyl, Var, Anvar, Oxandrins, Oxandrolonus, Oxandrolon.
Unlike most oral steroids, which are Class II steroids giving most of their anabolic effect by means other than the androgen receptor (AR), it seems that oxandrolone probably does have good binding to the AR, and is therefore a Class I steroid, while having little other effect. By itself it is considered to be a weak anabolic.
Partly this is due to its apparent lack of non-AR-mediated activity. This can be corrected of course by stacking with a Class II steroid such as Dianabol, Anadrol®, 4-AD, or nor-4-AD: the latter two steroids require high blood levels which are not obtained by oral use of the powders.
The other part of the reason for this is that bodybuilders make unfortunate and unreasonable comparisons when judging anabolic steroids. If say 8 tablets per day does little, then the drug is pronounced useless or weak by the user. But that is only 20 mg/day, or 140 mg/week. Does 140 mg/week testosterone give much results? No. Few anabolic steroids give dramatic results at that dose. Per milligram the potency is reasonable, but each individual tablet is weak because the dosage is small.
Because of its high price, very few bodybuilders have taken large doses of oxandrolone. There is a single case in the medical literature (Forbes et al.) where it is reported that a competitive athlete self-administered 150 mg oxandrolone per day with remarkable gains. This is of uncertain credibility because unless urinalysis was done to verify that no other steroids were taken, there is no way to be certain that the athlete did not actually take more drugs than he reported. In any case, at current prices, only the quite wealthy could afford such a dose.
Oxandrolone does not aromatize or convert to DHT, and has a longer half life than Dianabol - 8 hours vs. 4 hours. Thus, a moderate dose taken in the morning is largely out of the system by night, yet supplies reasonable levels of androgen during the day and early evening.
Oxandrolone shares the liver toxicity problems common to 17-alkylated steroids. At one time it was thought that it did not, but both clinical and practical experience with Oxandrin has shown that at doses of 40 mg/day and higher, liver toxicity is indeed an issue with prolonged use.
Alternative Description Anavar (Oxandrolone) 10mg, Generics Pharmacy, Bulgaria:
Anavar / Oxandrolone / Oxandrin
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Anavar was the old U.S. brand name for the oral steroid oxandrolone, first produced in 1964 by the drug manufacturer Searle. It was designed as an extremely mild anabolic, one that could even be safely used as a growth stimulant in children. One immediately thinks of the standard worry, "steroids will stunt growth". But it is actually the excess estrogen produced by most steroids that is the culprit, just as it is the reason why women stop growing sooner and have a shorter average stature than men. Oxandrolone will not aromatize, and therefore the anabolic effect of the compound can actually promote linear growth. Women usually tolerate this drug well at low doses, and at one time it was prescribed for the treatment of osteoporosis. As the opinions surrounding steroids began to change in the 1980's, prescriptions for oxandrolone began to drop. Lagging sales probably led Searle to discontinue manufacture in 1989, and it had vanished from U.S. pharmacies until recently. Oxandrolone tablets are again available inside the U.S. by BTG, bearing the new brand name Oxandrin. BTG purchased rights to the drug from Searle and it is now manufactured for the new purpose of treating HIV/AIDS related wasting syndrome.
Anavar is a mild anabolic with low androgenic activity. Its reduced androgenic activity is due to the fact that it is a derivative of dihydrotestosterone (DHT). Although one might think that this would make it a more androgenic steroid, it in fact creates a steroid that is less androgenic because it is already "5-alpha reduced". In other words, it lacks the capacity to interact with the 5-alpha reductase enzyme and convert to a more potent "dihydro° form. It is a simple matter of where a steroid is capable of being potentiated in the body, and with oxandrolone we do not have the same potential as testosterone, which is several times more active in androgen responsive tissues compared to muscle tissue due to its conversion to DHT. It essence oxandrolone has a balanced level of potency in both muscle and androgenic target tissues such as the scalp, skin and prostate. This is a similar situation as is noted with Primobolan and Winstrol, which are also derived from dihydrotestosterone yet not known to be very androgenic substances.
This steroid works well for the promotion of strength and duality muscle mass gains, although it's mild nature makes it less than ideal for bulking purposes. Among bodybuilders it is most commonly used during cutting phases of training when water retention is a concern. The standard dosage for men is in the range of 20-50mg per day, a level that should produce noticeable results. It can be further combined with anabolics like Primobolan and Winstrol to elicit a harder, more defined look without added water retention. Such combinations are very popular and can dramatically enhance the show physique. One can also add strong non-aromatizing androgens like Halotestin, Proviron or trenbolone. In this case the androgen really helps to harden up the muscles, while at the same time making conditions more favorable for fat reduction. Some athletes do choose to incorporate oxandrolone into bulking stacks, but usually with standard bulking drugs like testosterone or Dianabol. The usual goal in this instance is an additional gain of strength, as well as more quality look to the androgen bulk. Women who fear the masculinizing effects of many steroids would be quite comfortable using this drug, as this is very rarely seen with low doses. Here a daily dosage of 5mg should illicit considerable growth without the noticeable androgenic side effects of other drugs. Eager females may wish to addition mild anabolics like Winstrol, Primobolan or Durabolin. When combined with such anabolics, the user should notice faster, more pronounced muscle-building effects, but may also increase the likelihood of androgenic buildup.
Studies using low dosages of this compound note minimal interferences with natural testosterone production. Likewise when it is used alone in small amounts there is typically no need for ancillary drugs like Clomid/Nolvadex or HCG. This has a lot to do with the fact that it does not convert to estrogen, which we know has an extremely profound effect on endogenous hormone production. Without estrogen to trigger negative feedback, we seem to note a higher threshold before inhibition is noted. But at higher dosages of course, a suppression of natural testosterone levels will still occur with this drug as with any anabolic/androgenic steroid and therefore require post cycle therapy to restore the HPTA.
Anavar is also a 17alpha alkylated oral steroid, carrying an alteration that will put stress on the liver. It is important to point out however that dispite this alteration oxandrolone is generally very well tolerated. While liver enzyme tests will occasionally show elevated values, actual damage due to this steroid is not usually a problem. Bio-Technology General states that oxandrolone is not as extensively metabolized by the liver as other l7aa orals are; evidenced by the fact that nearly a third of the compound is still intact when excreted in the urine. This may have to do with the understood milder nature of this agent (compared to other l7aa orals) in terms of hepatotoxicity. One study comparing the effects of oxandrolone to other agents including as methyltestosterone, norethandrolone, fluoxymesterone and methAndriol clearly supports this notion. Here it was demonstrated that oxandrolone causes the lowest sulfobromophthalein (BSP; a marker of liver stress) retention among all the alkylated orals tested. 20mg of oxandrolone in fact produced 72% less BSP retention than an equal dosage of fluoxyrnesterone, which is a considerable difference being that they possess the same liver-toxic alteration. With such findings, combined with the fact that athletes rarely report trouble with this drug, most feel comfortable believing it to be much safer to use during longer cycles than most of other orals with this distinction. Although this may very well be true, the chance of liver damage still cannot be excluded, especially with hogher dosages.
At one time oxandrolone was also looked at as a possible drug for those suffering from disorders of high cholesterol or triglycerides. Early studies showed it to be capable of lowering total cholesterol and triglyceride values in certain types of hyperlipidemic patients, which initially this was thought to signify potential for this drug as a hypo-lipid (lipid lowering) agent. With further investigation we find however that while use of this drug can be linked to a lowering of total cholesterol values, it is such that a redistribution in the ratio of good (HDL) to bad (LDL) cholesterol occurs, usually moving values in an unfavorable direction. This would of course negate any positive effect that the drug might have on triglycerides or total cholesterol, and in fact make it a danger in terms of cardiac risk when taken for prolonged periods of time. Today we understand that as a group anabolic/androgenic steroids produce very unfavorable changes in lipid profiles, and are really not useful in disorders of lipid metabolism. As an oral c17 alpha alkylated steroid, oxandrolone is probably even more risky to use than an injectable esterified injectable such as a testosterone or nandrolone in this regard.
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