PRODUCT NAME: Glycomet/Glucophage
CONTENT: 100 Tabs/850mg
MANUFACTURER: India/USV Limited
Glucophage information and description. Glucophage is a trade name for the oral anti-hyperglycemic agent metformin HCL. Glucophage is generally used in the management of mature onset (Type-Il) diabetes and utilized when dietary management and exercise alone have not been able to control the disease, yet injectable insulin is not appropriate since this hormone is still present in the body. While the main activity of Glucophage (metformin HCL) is the increased utilization of glucose, it does not directly mimic the action of insulin.
Glucophage side effects. While Glucophage is considered much safer than insulin, it is not without own unique risks. The most serious complication is the possible development of lactic acidosis. This is an often-fatal metabolic disorder involving (among other factors) an increase in lactate levels (lactic) and a pronounced decrease in blood pH (acidosis). The package insert of Glucophage displays the additional warning: the administration of oral hypoglycemics may be associated with increased cardiovascular mortality as compared to treatment with diet alone or diet with insulin. The risk for severe side effects of Glucophage are increased in people suffering from liver dysfunction or who drink excessive alcohol. Or those with renal dysfunction, noting impaired creatine clearance (a serum concentration above 1,2mg per 100 ml is considered the cut-off point for treatment). A number of other "minor" side effects of Glucophage may include, but are not limited to, anorexia, nausea, vomiting, diarrhea, metallic taste, fatigue, weakness and malabsorbtion of vitamin B12. Quite often these side effects effects will subside if the dosage of Glucophage (metformin HCL) is lowered.
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